Melanotan I
Tanning; approved for rare sun sensitivity
Afamelanotide (Scenesse)
Match every finding to its exact substance, formulation, route and study population. A related molecule or approved medicine does not validate a catalog vial.
Color key
At a glance
Why people take it. And what backs it up.
-
Get a deeper tan
Early human studies
Tanners inject gray-market vials alongside sun or sunbeds, often choosing it over Melanotan II hoping for milder side effects; health agencies warn against unlicensed melanotan.
Sources (5)
-
ForumReddit r/Melanotan1: “Epic Farmer’s Tan” (April 2026) (opens in a new tab)
“My forearms, hands, legs and face are already the kind of deep gold/olive I normally don’t achieve until late summer.”
-
ForumReddit r/Melanotan1: “How long until tan develops?” (March 2026) (opens in a new tab)
“have taken MT2 for years and now switched to MT1 as I dont enjoy the side effects of MT2.”
-
TrialLevine et al., JAMA, 1991 (28 men; PubMed abstract) (opens in a new tab)
“Human skin darkens as a response to a synthetic melanotropin given by subcutaneous injection.”
-
TrialDorr et al., Archives of Dermatology, 2004 (PubMed abstract) (opens in a new tab)
“there was significantly enhanced tanning of the back in the MT-1 group, and this was maintained at least 3 weeks longer than the tanning in the sunlight-only controls”
-
“Multiple national health organizations have issued safety warnings regarding the use of melanotan I and II.”
-
-
Tolerate sunlight without pain
Implant approved for rare sun sensitivity
Approved as the Scenesse implant for adults with a rare inherited disease that makes light painful; it lets them spend longer in light without pain.
Sources (3)
-
LabelScenesse prescribing information (FDA, revised 08/2024) (opens in a new tab)
“SCENESSE is a melanocortin 1 receptor (MC1-R) agonist indicated to increase pain free light exposure in adult patients with a history of phototoxic reactions from erythropoietic protoporphyria (EPP)”
-
“was associated with an increased duration of sun exposure without pain and improved quality of life in patients with erythropoietic protoporphyria”
-
ForumAmerican Porphyria Foundation, patient story (Margie Rose, EPP) (opens in a new tab)
“I got my first Scenesse implant for EPP 15 days ago. Since then, I’ve experienced the sun on my face with no pain!!”
-
-
Restore color in vitiligo
Small trial; not approved for this
Some people with vitiligo use it with light therapy, hoping white patches regain color faster; the trial used the implant, not vials.
Sources (3)
-
VendorTailor Made Compounding peptide catalog (compounding pharmacy), dosing chart (opens in a new tab)
“Melanotan I 5mL at 2000mcg/mL 0.15mL daily with UVB light exposure Patient preference Subcutaneous injection into the abdomen Injection Vitiligo”
-
“I’ve tried m1 and m2, and neither had an effect on my vitiligo spots.”
-
TrialLim et al., JAMA Dermatology, 2015 (55 adults; PubMed abstract) (opens in a new tab)
“A combination of afamelanotide implant and NB-UV-B phototherapy resulted in clinically apparent, statistically significant superior and faster repigmentation compared with NB-UV-B monotherapy.”
-
Evidence briefing
Sources checkedWhat the sources support.
Afamelanotide is a long-acting alpha-MSH analog commonly called Melanotan I. FDA approval is for the specified 16 mg Scenesse subcutaneous implant, administered by a trained clinician to increase pain-free light exposure in adults with erythropoietic protoporphyria (EPP). It does not approve online Melanotan-I vials or cosmetic tanning use.
Approval attaches to the tested implant, indication, adults with EPP and trained-clinician administration; the shared nickname does not establish that vendor products contain afamelanotide or match Scenesse.
The research. What’s been studied.
-
Human evidence
EPP light tolerance
The FDA-approved Scenesse implant increases pain-free light exposure in adults with EPP; it is given by a trained clinician.
-
Human evidence
Skin pigmentation
Afamelanotide stimulates pigmentation, but the approved use is EPP and does not make it a cosmetic tanning treatment.
-
Early human studies
Vitiligo research
Afamelanotide has been studied with light therapy for vitiligo; this is not an approved indication.
What do these labels mean?
- Human evidence: approved-drug data or larger human studies, within the populations and uses studied.
- Early human studies: small, preliminary or limited human studies.
- Animal & lab studies: animal or laboratory findings that do not establish effects in people.
- Unverified: a proposed use or claim without verified supporting clinical evidence.
How each claim was reviewed (4)
Reported effects and evidence.
A citation may support, qualify or correct a claim. Read the study scope; a laboratory result is not an established benefit in people. Each review covers a claim as it was first collected; the tiles above show the collection’s current wording.
-
Approved-product pigment pharmacology; misleading protection headline
Review of “Protective tan”
Afamelanotide increases eumelanin. This does not establish safe recreational tanning or substitute for sun protection.
Limitations and applicability. Pigmentation is not a guarantee of safe tanning or skin-cancer prevention; approved implant population and precautions matter.
Original collected claim and review history
Original title: Protective tan
Increases eumelanin, the dark pigment that protects skin from UV.
Original label: proven. Preserved for traceability; the reviewed wording above qualifies this record.
Record melanotan-i:benefit:1 · Annotated 2026-10-01 · Review method
-
FDA-approved implant indication
Review of “Sun tolerance in EPP”
Scenesse implants increase pain-free light exposure in adults with EPP and a history of phototoxic reactions.
Limitations and applicability. Indication is adult EPP with phototoxic reactions; approval does not cover vendor research injections.
Original collected claim and review history
Original title: Sun tolerance in EPP
Approved to let people with a painful sunlight disorder spend more time in light.
Original label: proven. Preserved for traceability; the reviewed wording above qualifies this record.
Record melanotan-i:benefit:2 · Annotated 2026-10-01 · Review method
-
Human randomized combination study
Review of “Vitiligo repigmentation”
A randomized study investigated afamelanotide implants plus narrowband UV-B for vitiligo repigmentation.
Limitations and applicability. Combination with NB-UVB and selected skin types; not approval for vitiligo or isolated peptide efficacy.
Original collected claim and review history
Original title: Vitiligo repigmentation
Studied with light therapy to restore color in vitiligo patches.
Original label: early. Preserved for traceability; the reviewed wording above qualifies this record.
Record melanotan-i:benefit:3 · Annotated 2026-10-01 · Review method
-
Receptor pharmacology; comparative clinical safety unresolved
Review of “More targeted than Melanotan II”
Afamelanotide acts at MC1R. A comparative claim about fewer appetite or sexual effects requires a specific study.
Limitations and applicability. MC1R agonism is supported; fewer libido/appetite effects versus MT-II needs a direct comparative source.
Original collected claim and review history
Original title: More targeted than Melanotan II
Mainly acts on skin pigment cells, with fewer effects on appetite and libido.
Original label: proven. Preserved for traceability; the reviewed wording above qualifies this record.
Record melanotan-i:benefit:4 · Annotated 2026-10-01 · Review method
The research in detail
Evidence category
FDA-approved (US)
The approved afamelanotide implant increases pain-free light exposure in adults with EPP. That clinical evidence and approval concern the regulated implant and its EPP indication; they do not establish quality or safety of unverified seller products or cosmetic tanning.
Evidence is assessed claim by claim above. Regulatory approval, study design, findings and relevance are separate questions; there is no single evidence score.
Risks and unknowns. What to know first.
Collected cautions follow. These are not an exhaustive or independently validated safety assessment; claim references do not automatically support every caution.
- Nausea, headache, darkening of moles and skin.
- Regular skin checks are required on the approved drug.
- Injected research versions lack the implant’s controlled release.
What people report
-
User reports
Severe nausea and vomiting are reported, even at small doses while “preloading”.
Source: Reddit r/Melanotan1: “Extreme nausea” (May 2026) (opens in a new tab)
-
User reports
Users report random white spots appearing as the tan develops.
Source: Reddit r/Melanotan1: “White spots” (January 2026) (opens in a new tab)
-
User reports
A user with allergies reported mild headaches and evening shivering around 200 mcg of melanotan I, before a later hospital visit for an allergic reaction to melanotan II.
Source: Reddit r/Melanotan2: “Allergic reaction to MT2” (August 2026) (opens in a new tab)
Show all 4 cautionsShow fewer cautions
-
Regulator
It is illegal to sell or supply melanotan injections in the UK, and Cancer Research UK says melanotan products are not safe to use.
Source: Cancer Research UK: Tanning, fake tan and Melanotan (opens in a new tab)
Published dosing records. What the approved label says.
Historical label and trial records for the named product, route, population and indication. These records are not a personal schedule or a validated regimen for a catalog vial. Source attribution does not establish applicability.
Scenesse
Adults with erythropoietic protoporphyria (EPP), a rare condition that makes light exposure painful, to increase pain-free time in light
Source: Scenesse prescribing information (FDA, revised 08/2024) (opens in a new tab)
- Every 2 months
- 16 mg
- How
- Implant placed under the skin, just above the front of the hip bone
- How often
- One implant every 2 months
- How long
- No set length
- The approved product is a slow-release 16 mg implant (a rod about 1.7 cm long) placed under the skin through a special cannula, not an injectable liquid. A health care professional who has completed the maker’s (Clinuvel’s) training inserts it.
- The patient is watched for 30 minutes after insertion, and the dressing stays on for 24 hours.
- Sun and light protection continues during treatment.
- The EU label (updated 10/2025) gives one implant every 2 months before and during times of stronger sunlight. It sets no yearly cap: a specialist at a porphyria centre decides how many implants and for how long, and it notes limited data on 4–6 implants a year.
These are the label’s doses for the approved medicine, started and adjusted by a prescriber. A research vial is not that medicine: no regulator has checked what’s in it, or how much.
Community protocols. Reported online. Not clinically validated.
Community reports Collection date: 30 Sep 2026Grey-market melanotan I (research vials, not the approved implant) is used like melanotan II: about 250–500 mcg injected daily for roughly 1–2 weeks with sun or sunbed exposure, then 250–500 mcg once or twice a week to maintain.
More about this
Many only dose on sun days, and some push to 0.75–1 mg while others start as low as 50–100 mcg.
Loading, then maintenance
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Forum: Reddit r/Melanotan1: “4 weeks of progress MT1” (June 2026)
- Forum: Reddit r/Melanotan1: “Drop your routines in the comments please” (May 2026)
- Forum: Reddit r/Melanotan2: “MT1 results” (September 2026)
- Forum: Reddit r/Melanotan2: “Melanotan-1 Guidance” (September 2026)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- Loading: 250–500 mcg. Maintenance: 250–500 mcg.
- How often
- Loading: every day. Maintenance: once or twice a week.
- Route
- Injection under the skin
- Timing
- Before sun or sunbed exposure (often 30–60 minutes of sun)
- How long
- Loading about 1–2 weeks, or until the wanted colour
- Ramp
- 250 mcg on day 1 to test tolerance, then 500 mcg
- Mixing
- 10 mg vial + 2 mL bacteriostatic water is typical
- Some choose it over melanotan II hoping for fewer side effects and fewer new freckles.
- Often started in spring (April or May) for the summer season.
Sources (4)
-
ForumReddit r/Melanotan1: “4 weeks of progress MT1” (June 2026) (opens in a new tab)
“Loaded for 2 weeks with no real progress or tan lines. 250mcg day 1 to test tolerance, 500mcg the day after that.”
-
ForumReddit r/Melanotan1: “Drop your routines in the comments please” (May 2026) (opens in a new tab)
“I hear 500mcg with an hour of sun daily is enough to build a tan, and then 250-500mcg 1-2x a week for an hour is enough to maintain.”
-
ForumReddit r/Melanotan2: “MT1 results” (September 2026) (opens in a new tab)
“Was running every day for 2 weeks and now dose 500mcg about twice a week with tanning.”
-
ForumReddit r/Melanotan2: “Melanotan-1 Guidance” (September 2026) (opens in a new tab)
“you get a vial to room temperature, wipe the top with a alcohol wipe let it dry, draw 2ml of bac water”
Only on sun or sunbed days
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Forum: Reddit r/Melanotan1: “1 month on Melanotan 1” (August 2026)
- Forum: Reddit r/Melanotan2: “Mt1 after 2,5 weeks” (August 2026)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- 250–500 mcg
- How often
- Only on days with UV exposure (about 3–4 times a week)
- Route
- Injection under the skin
- Timing
- Before 30–60 minutes of sun or a sunbed
- How long
- Through the summer
Sources (2)
-
ForumReddit r/Melanotan1: “1 month on Melanotan 1” (August 2026) (opens in a new tab)
“I only use it on days I tan outside or go tanning bed 250mcg, so maybe 3-4 times a week.”
-
ForumReddit r/Melanotan2: “Mt1 after 2,5 weeks” (August 2026) (opens in a new tab)
“500 mcg only on the days when I get sun exposure (between 30 and 60 minutes).”
Show all 4 protocolsShow fewer protocols
Higher dose (0.75–1 mg or more)
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Forum: Reddit r/Melanotan1: “Very Fair Skin - Plateau after 2-3 weeks” (June 2026)
- Forum: Reddit r/Melanotan1: “Why I don’t think blasting high doses of MT-1 makes sense” (August 2026)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- 750 mcg–1 mg or more
- How often
- Most days
- Route
- Injection under the skin
- Timing
- Before sun
- Ramp
- Stepped up after a plateau at 500 mcg
- Other users argue high doses waste product because the skin’s receptors are already saturated.
Sources (2)
-
ForumReddit r/Melanotan1: “Very Fair Skin - Plateau after 2-3 weeks” (June 2026) (opens in a new tab)
“For the past 3 weeks I’ve done around 500mcg 3-4 days per week, recently been doing 750mcg-1mg subs.”
-
“See so many people taking 1mg or more a day thinking it’s going to make them dark overnight”
Very slow start
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Forum: Reddit r/Melanotan2: “Allergic reaction to MT2” (August 2026; describes earlier MT1 use)
- Forum: Reddit r/Melanotan2: “MT1 dosage” (August 2026)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- 50–100 mcg, rising to about 300 mcg
- How often
- Daily for about 1–2 weeks, then twice a week
- Route
- Injection under the skin
- Timing
- Some take an antihistamine about 40 minutes before
- How long
- About 2 weeks
- Ramp
- Gradual increase over about 2 weeks
- Used by people worried about nausea or allergic-type reactions.
Sources (2)
-
“I started very slow at around 50mcg and over the two week span I went up to 300mcg.”
-
ForumReddit r/Melanotan2: “MT1 dosage” (August 2026) (opens in a new tab)
“I’ve started doing 100mcg daily, planning to do this for 7 days then just do it twice a week.”
Where the numbers come from
Forum practice copies the melanotan II “loading and maintenance” pattern at similar microgram doses. The approved form of the drug, afamelanotide, is a slow-release implant used for a rare light-sensitivity disease; grey-market users do not copy that dosing.
Home-made sprays and serums
Home-made nasal spray. Community recipes. Not tested.
Original source recordsHide
A few users take melanotan I (or tanning peptides generally) as vendor or home-made nasal sprays; one household mixes a 10 mg vial with 1 mL bacteriostatic water and uses one puff a day. Community only, and the key recipe may refer to melanotan II.
Best evidence: Community only (Reddit r/Peptides, 2025). No trial or approved nasal product; the approved form (Scenesse) is an implant.
Collected strength records
-
1 mg per sprayFringe
Workings 10 mg ÷ 1 mL = 10 mg/mL; × 0.1 mL = 1 mg per spray. The poster never worked out the dose or gave a spray size, so 0.1 mL is assumed (approved sprays deliver about 0.1 mL per press). The post does not say whether it is melanotan I or II.
Sources (3)
-
ForumReddit r/Peptides, u/Wafty-1271 (comment, 2025-11-01) (opens in a new tab)
“Have to confess we’ve never worked it out. 1ml BAC in 10mg vial.”
-
ForumReddit r/Peptides, u/Wafty-1271 (comment, 2025-11-01) (opens in a new tab)
“The spray works fine for tanning purposes. Just one puff each day and by week 2 or 3 if you’ve seen some sun the tan will start building nicely.”
-
ManufacturerDesmopressin Nasal Spray, USP – FDA label (Apotex), DailyMed (opens in a new tab)
“Desmopressin nasal spray pump delivers 10 mcg (0.1 mL) of desmopressin acetate per spray.”
-
10 mg vial + 1 mL bacteriostatic water, one puff a day
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
- Forum: Reddit r/Peptides, u/Wafty-1271 (comment, 2025-11-01)
- Forum: Reddit r/Peptides, u/Wafty-1271 (comment, 2025-11-01)
- Forum: Reddit r/Peptides, u/Alert_Ad7433 (comment, 2025-04-11)
Batch: 1 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| Melanotan (vial) | 10 mg | Active |
| Bacteriostatic water | 1 mL | Liquid / preservative |
- How it’s used
- One puff a day; after about a month, every other day. Taking it just after breakfast helped with nausea.
- Per dose
- Not worked out by the poster.
- Preservative
- Bacteriostatic water.
- Posted in a melanotan I thread, but the poster does not say whether their spray is melanotan I or II.
Sources (3)
-
ForumReddit r/Peptides, u/Wafty-1271 (comment, 2025-11-01) (opens in a new tab)
“The spray works fine for tanning purposes. Just one puff each day and by week 2 or 3 if you’ve seen some sun the tan will start building nicely.”
-
ForumReddit r/Peptides, u/Wafty-1271 (comment, 2025-11-01) (opens in a new tab)
“Have to confess we’ve never worked it out. 1ml BAC in 10mg vial.”
-
ForumReddit r/Peptides, u/Alert_Ad7433 (comment, 2025-04-11) (opens in a new tab)
“I started using it a month ago and have been pleased.”
How the method was put together, step by step with its sources
Editorial synthesis and reported strength comparison
This synthesized method combines source records. It has not been validated for preparation, sterility, compatibility, absorption or storage. Select a reported strength to inspect the arithmetic; no strength is selected for you.
1 mg per spray
Makes 1 mL · about 5 sprays (with a 0.1 mL pump)
Synthesized quantities and equipment
- 10 mg Melanotan I
- 1 mL bacteriostatic water
- Liquid, which people disagree on: sterile saline (gentler, but no preservative), bacteriostatic water (preserved, but can burn), or a mix of the two.
- An empty metered nasal spray bottle. Many are sold as about 0.1 mL per press, but users report 0.05–0.2 mL, so check yours.
- New sterile syringes to measure and move liquid. On a U-100 insulin syringe, 100 units is 1 mL, so 1 unit is 0.01 mL.
- Alcohol prep pads, for the vial stopper and the spray tip.
Synthesized steps · not validated
- Check your pump first: spray a measured amount of water through it and count the presses. Users report about 0.05–0.2 mL per press.
- Wash your hands. Wipe the vial’s rubber stopper with an alcohol pad and let it dry before piercing it.
- With a new sterile syringe, add a little of the liquid slowly, aiming it down the inside wall of the vial, not onto the powder.
- Swirl or roll the vial gently until the powder dissolves; don’t shake it. Don’t use it if it’s cloudy, discoloured or has particles.
- Draw the dissolved peptide back into the syringe and add it gently to the spray bottle.
- Rinse the vial with a little more of the liquid and add that to the bottle too, so no peptide is left behind.
- Make the bottle up to the full batch volume with the rest of the liquid.
- Fit the pump and press it into the air until a fine mist appears; labels say 4–6 presses. Re-prime after 3–7 days unused.
- Label the bottle with the date you mixed it and its strength.
- Before each dose, blow your nose gently. Close one nostril and aim the tip toward the back of your head, not the middle wall.
- Labels differ: some say breathe in gently as you press, others hold your breath. Try not to sneeze or blow your nose straight afterwards.
- Afterwards, wipe the tip with an alcohol wipe, put the cap back on and keep the bottle upright.
- Each spray
- 1 mg (1,000 mcg) per 0.1 mL spray
- Keeps
- Fridge (2–8 °C), upright; don’t freeze. No tested shelf life: pharmacy defaults are 14 days unpreserved, 35 days preserved; saline dilutes bacteriostatic water’s preservative.
- How it’s used
- One press per nostril at a time: a nostril holds about 0.1 mL, at most 0.15 mL, and more runs out or is swallowed.
Good to know
- Bacteriostatic water contains 0.9–1.1% benzyl alcohol as a preservative. Its label covers mixing injections, not nasal use; EU labels warn of allergic reactions.
- Some use store-bought saline nasal spray for its preservatives: often benzalkonium chloride, which can irritate the nose with long use, and sometimes benzyl alcohol.
- Never tap water: it is not sterile, and CDC researchers warn against it for nasal rinsing.
This method is a guide put together from the sources cited for each item (drug labels, pharmacy and CDC rules, research reviews and community recipes); it is not anyone’s tested protocol. The method’s sources
What people report
-
User reports
Users say a nasal spray causes less nausea only because less is absorbed.
Source: Reddit r/Peptides – ‘Melanotan I spray vs injection – reduced nausea?’ (2025) (opens in a new tab)
Research notes
Grey-market melanotan I is a research-vial product, unrelated in dosing to the approved afamelanotide implant. Many users also take melanotan II, retatrutide or other peptides, so side effects are hard to attribute. Doses in forum posts are sometimes written in “units”, which depend on how the vial was mixed.
Nasal spray
Melanotan I vs II is unclear in the main source.
What it is. In plain English.
Afamelanotide is an alpha-MSH analog approved as a specific implant for adults with erythropoietic protoporphyria, not for cosmetic tanning.
A long-acting alpha-MSH analog also commonly called Melanotan I. FDA approval applies to the specified 16 mg Scenesse subcutaneous implant administered by a trained clinician for adults with erythropoietic protoporphyria (EPP), not to online Melanotan-I vials or tanning use.
Afamelanotide stimulates pigmentation. The approved Scenesse implant is used to increase pain-free light exposure in adults with EPP; this does not establish a cosmetic tanning use or approve seller vials.
Reviewed 2026-10-01.
Structure. What it really looks like.
Experimental
Melanotan I (afamelanotide, coral) bound to the human melanocortin-1 receptor (gray). Also part of the experiment, but not drawn: a G protein and two antibody fragments.
Missing parts
- The peptide’s first amino acid and the caps on both its ends aren’t in the model, and the second amino acid’s side chain is cut short.
- A calcium ion that bridges the peptide and the receptor in the experiment isn’t drawn.
7F4H, Ma et al., 2021. Rendered with Mol* (Sehnal et al., 2021) from RCSB PDB data (Berman et al., 2000).
Specs. The facts at a glance.
- Length
- 13 amino acids
- Sequence
- Ac-S-Y-S-Nle-E-H-f-R-W-G-K-P-V-NH₂
- Sold as
- Melanotan I 10 mg
- Regulatory status
- FDA-approved as the Scenesse 16 mg implant to increase pain-free light exposure in adults with EPP. The approval does not cover cosmetic tanning or vendor Melanotan-I products.
- Also known as
- Afamelanotide (Scenesse)
Sources. What this page rests on.
Every source behind this page, with what it says and when it was checked, is in the Source library.
Melanotan I in the Source library
Original overview and research notes · annotated 2026-10-01
Historical collection text. Read alongside the claim corrections above; identity or evidence qualifications may supersede this wording.
Tanning and sun protection
An approved tanning peptide used as medicine for a rare sunlight-sensitivity disease.
The skin hormone α-MSH with two amino acids swapped so it lasts longer. A straight 13-amino-acid chain.
It targets MC1R on pigment cells and increases eumelanin, the dark, protective pigment. It’s more selective than Melanotan II, with fewer effects on sexual function and appetite.
Trials in erythropoietic protoporphyria (EPP), a disease that makes sunlight painful, increased the time patients could spend in light. The approved form is a slow-release implant under the skin.
Original status record: FDA-approved in 2019 as Scenesse (implant) for EPP; approved in the EU since 2014.