Peptide Field Book

Reading settings

Choose a comfortable text size and appearance. Your choices are saved on this device.

Bronchogen

Taken for lung support

Khavinson bioregulator

Match every finding to its exact substance, formulation, route and study population. A related molecule or approved medicine does not validate a catalog vial.

Animal / laboratory evidence
AEDL
Schematic illustration · View structure evidenceAEDL
Color key
NonpolarAromaticPositive chargeNegative chargePolar Copper ion D-form or non-natural

At a glance

Why people take it. And what backs it up.

  1. Support lungs and airways

    People report it, not studied

    Sold as a Russian lung ‘bioregulator’ and taken in month-long courses to support breathing, including after smoking or chest infections.

    Sources (5)
  2. Ease bronchitis or COPD

    Animal studies only

    Some with chronic bronchitis, emphysema, COPD or asthma try it hoping to breathe easier.

    Sources (4)

Evidence briefing

Sources checked

What the sources support.

Bronchogen is the tetrapeptide Ala-Glu-Asp-Leu in the Khavinson peptide-bioregulator program. A PubMed-indexed study tested it in rats with experimentally induced obstructive lung pathology and reported tissue changes; this does not demonstrate treatment of human COPD. It is not an approved drug, and no human clinical outcome evidence was identified.

Keep in mind

The lung evidence is an induced rat model from the developer research network; disease-model findings cannot establish a benefit or safe route in people.

Identity and research status reviewRead the original sources

The research. What’s been studied.

  • Animal & lab studies

    Rat lung-model research

    A rat study reported changes in bronchial epithelium after experimental lung injury; this does not establish repair of human airways or treatment of COPD.

  • Unverified

    Mucus-clearance claim

    Support for airway mucus clearance is a proposed or marketed claim, not a demonstrated human clinical benefit.

What do these labels mean?
  • Human evidence: approved-drug data or larger human studies, within the populations and uses studied.
  • Early human studies: small, preliminary or limited human studies.
  • Animal & lab studies: animal or laboratory findings that do not establish effects in people.
  • Unverified: a proposed use or claim without verified supporting clinical evidence.
How each claim was reviewed (2)

Reported effects and evidence.

A citation may support, qualify or correct a claim. Read the study scope; a laboratory result is not an established benefit in people. Each review covers a claim as it was first collected; the tiles above show the collection’s current wording.

  1. Preclinical rat lung-injury experiments

    Review of “Airway repair”

    Bronchogen affected bronchial-remodeling/inflammation measures in rat nitrogen-dioxide-exposure models.

    Limitations and applicability. Correct preclinical scope; specify nitrogen-dioxide-exposure injury model and developer-associated research.

    Original collected claim and review history

    Original title: Airway repair

    Studied in rat models of lung injury by the developer’s group.

    Original label: animal. Preserved for traceability; the reviewed wording above qualifies this record.

    Record bronchogen:benefit:1 · Annotated 2026-10-01 · Review method

  2. Preclinical histology; mucus-clearance inference

    Review of “Mucus clearance”

    Rat studies described epithelial/ciliated-cell changes; a human mucus-clearance benefit is unestablished.

    Limitations and applicability. Restored ciliated-cell histology is not direct evidence of improved mucus clearance in humans.

    Original collected claim and review history

    Original title: Mucus clearance

    Claimed to support the cells lining the airways.

    Original label: claimed. Preserved for traceability; the reviewed wording above qualifies this record.

    Record bronchogen:benefit:2 · Annotated 2026-10-01 · Review method

The research in detail

Evidence category

Mostly animal and cell studies

A study reported bronchial tissue changes in rats with experimentally induced obstructive lung pathology. This does not demonstrate treatment of human COPD or establish a safe clinical route. No controlled human outcome evidence was identified.

Evidence is assessed claim by claim above. Regulatory approval, study design, findings and relevance are separate questions; there is no single evidence score.

Risks and unknowns. What to know first.

Collected cautions follow. These are not an exhaustive or independently validated safety assessment; claim references do not automatically support every caution.

  • Unknown.

What people report

Read this first: what “research use only” means

Published dosing records. No established dose.

Historical label and trial records for the named product, route, population and indication. These records are not a personal schedule or a validated regimen for a catalog vial. Source attribution does not establish applicability.

Bronchogen (the peptide Ala-Glu-Asp-Leu) has only been tested in lab cell cultures and in rats with lab-induced lung damage. PubMed and ClinicalTrials.gov list no human trial, and no drug regulator has approved it.

Any dose you see online for it is a guess, not a tested dose.

Community protocols. Reported online. Not clinically validated.

Community reports Collection date: 30 Sep 2026

Two forms circulate: oral capsules sold as a Russian supplement, taken as 1–2 capsules once or twice a day for 20–30 days and repeated every 4–6 months, and 20 mg research vials injected under the skin at about 500 mcg–1 mg a day for 20–40 days.

More about this

Community data are thin: a handful of Reddit self-experiments, and one of them was later repackaged as an influencer’s protocol.

Not testedFrequently encountered in reviewed sources

Oral capsules (label directions)

Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.

Frequency labels describe this collection, not a measured population. Contradictory records remain available.

Details and sourcesHide details
Dose
1–2 capsules (the peptide amount per capsule is not stated on the labels seen; one forum user estimated about 2.5 mg)
How often
Once or twice a day
Route
Oral (capsules)
Timing
With or before meals (labels differ)
How long
20–30 days (some labels say 1 month)
Cycle
Repeat after 3–6 or 4–6 months
  • Sold in 60-capsule packs as a Russian dietary supplement in the Khavinson “cytogen” product line.
  • One seller’s label suggests following the course with a natural bronchial peptide complex (Taxorest).
  • Sellers’ ingredient lists differ slightly (one lists leucine, another arginine).
Sources (4)

Not testedCommon

Injection from research vials

Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.

Frequency labels describe this collection, not a measured population. Contradictory records remain available.

Details and sourcesHide details
Dose
500 mcg–1 mg a day (a few use 2 mg)
How often
Once a day; one version runs 6 days on, 1 day off
Route
Injection under the skin (belly or buttock)
Timing
Often in the evening, about 2 hours after the last meal; some inject on an empty stomach
How long
20–40 days (the “advanced” version runs 7 weeks)
Cycle
About a month off between courses in one report; label-style 3–6 month breaks are also cited
Ramp
Some start at 250–500 mcg and move up to 1 mg
Mixing
20 mg vial + 3 mL bacteriostatic water: 1 mg = 0.15 mL (15 units); 500 mcg = 7.5 units
  • Jay Campbell’s “beginner” (500 mcg a day for 40 days, evening) and “advanced” (1,000 mcg a day, 6 days on and 1 off, for 7 weeks) protocols match one Reddit user’s 2023–2024 self-experiment almost exactly.
  • Jay Campbell also describes a ready-made pen at 2 mg a day (10 doses per pen).
  • Users who self-tested with home spirometers reported modest, uncontrolled changes.
Sources (4)
Show all 3 protocolsShow fewer protocols

Not testedSometimes seen

Low-dose “maintenance” (vendor owner’s rule of thumb)

Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.

Frequency labels describe this collection, not a measured population. Contradictory records remain available.

Details and sourcesHide details
Dose
100 mcg a day for maintenance; 0.5 mg (some say 0.5–1 mg) a day for a “diseased organ”
How often
Once a day
Route
Injection under the skin (research vials)
How long
40–60 days for the 0.5 mg version
  • Attributed on Reddit to Jean-François Tremblay, owner of the Canadian peptide seller CanLab, as a general rule for all short bioregulators, not Bronchogen specifically.
Sources (3)

Where the numbers come from

The capsule directions are the Russian manufacturers’ label directions (Khavinson “cytogen” line, sold as supplements). Injectable doses have no published basis: forum users derived them from a vendor owner’s rule of thumb for all bioregulators (100 mcg maintenance, 0.5 mg for 40–60 days) and from one Reddit user’s 500 mcg-then-1 mg self-experiment, which an influencer (Jay Campbell) then published as his protocol.

Research notes

Thin data: fewer than ten Reddit threads, mostly single-user reports. Capsule labels do not state how much peptide each capsule holds, so capsule and injection doses cannot be compared. Jay Campbell’s published protocol appears to be copied from one Reddit user’s experiment. Sellers’ ingredient lists differ (leucine vs arginine). No regulator statements specific to Bronchogen were found.

What it is. In plain English.

A bioregulator peptide marketed for lung and airway health.

Ala-Glu-Asp-Leu, from the same St. Petersburg bioregulator program as Epitalon and Cartalax.

Claimed to regulate gene activity in the cells lining the airways, supporting mucus clearance and repair.

Reviewed 2026-10-01.

Structure. Nothing to show yet.

No experimental 3D structure of Bronchogen is in the .

No chain in the Protein Data Bank consists of its four amino acids, Ala-Glu-Asp-Leu.

Checked 30 Sep 2026.

Specs. The facts at a glance.

Length
4 amino acids
Sequence
AEDL
Sold as
  • Bronchogen 10 mg
Regulatory status
Not approved. .
Also known as
Khavinson bioregulator

Sources. What this page rests on.

Every source behind this page, with what it says and when it was checked, is in the Source library.

Bronchogen in the Source library

Original overview and research notes · annotated 2026-10-01

Historical collection text. Read alongside the claim corrections above; identity or evidence qualifications may supersede this wording.

Lung and airway support (claimed)

A bioregulator peptide marketed for lung and airway health.

Ala-Glu-Asp-Leu, from the same St. Petersburg bioregulator program as Epitalon and Cartalax.

Claimed to regulate gene activity in the cells lining the airways, supporting mucus clearance and repair.

Animal and cell studies from the developer’s group, including rat models of lung injury. No independent human trials.

Original status record: Not approved. Research chemical.

More in Longevity.

Glossary

Research use only (RUO)

A label for chemicals sold for lab experiments. It lets products reach the market without the testing and manufacturing controls required for drugs.

Glossary

Protein Data Bank (PDB)

The free worldwide archive of 3D structures of proteins and other molecules measured in experiments. Each entry has a four-character code, like 7KI0.