N-Acetyl Selank Amidate
Taken to ease anxiety
Modified Selank
This entry is the N-acetyl amidated derivative. Parent Semax/Selank studies and approval records do not establish this derivative’s efficacy, safety or approval.
Color key
At a glance
Why people take it. And what backs it up.
-
Calm anxiety
People report it, not studied
Most take a nasal spray or small shot hoping to ease anxiety without sedation; plain Selank is approved in Russia, but not this form.
Sources (5)
-
ForumReddit r/Nootropics: “N-Acetyl Selank Amidate help” (June 2026) (opens in a new tab)
“I started N-Acetyl Selank Amidate inject last day, and took 300mcg yesterday morning and 300mcg today for my long-time anxiety”
-
“selank around mid-afternoon (~400mcg) when my anxiety/rumination kicks up”
-
“I never tried peptides so i bought n-acetyl selank amidate in nasal spray, 300mcg per spray.”
-
“some of this could be due to use of long-acting forms of Selank as well, which reduces anxiety without sedating.”
-
“Показания к применению: Тревожные состояния: • немотивированная тревога, беспокойство; • приступы паники;”
In English: Indications for use: anxiety states: unexplained anxiety, restlessness; panic attacks.
-
Evidence briefing
Sources checkedWhat the sources support.
The catalogue names N-acetyl Selank amidate, a modified product, rather than plain Selank. FDA lists Selank acetate (TP-7) as a separate bulk substance and says it lacks important safety information for administration to humans; that FDA assessment is not proof of approval or of clinical evidence for the N-acetyl amidate. A Russian-market nasal Selank product does not transfer its status to these modified forms. No FDA or EU drug approval was identified.
Names and salts/terminal modifications are inconsistent in the peptide market, and clinical claims for plain Selank cannot be assumed to apply to acetate or amidated seller variants.
The research. What’s been studied.
Clinical benefit unverified
TapClick a dotted word to see what it means.
-
No verified benefit for this form
The Selank amidate listed here has no verified clinical evidence. Findings for plain Selank cannot be assumed to apply to this modified form.
What do these labels mean?
- Human evidence: approved-drug data or larger human studies, within the populations and uses studied.
- Early human studies: small, preliminary or limited human studies.
- Animal & lab studies: animal or laboratory findings that do not establish effects in people.
- Unverified: a proposed use or claim without verified supporting clinical evidence.
How each claim was reviewed (4)
Reported effects and evidence.
A citation may support, qualify or correct a claim. Read the study scope; a laboratory result is not an established benefit in people. Each review covers a claim as it was first collected; the tiles above show the collection’s current wording.
-
Small human parent-compound comparison; modified-form mismatch
Review of “Less anxiety”
Small studies compared plain Selank with benzodiazepines. Their results cannot be assigned to N-acetyl amidated Selank.
Limitations and applicability. Entry describes N-acetyl amidate; parent comparisons do not establish equivalent efficacy or noninferiority of derivative.
Original collected claim and review history
Original title: Less anxiety
Russian trials in generalized anxiety found effects comparable to a benzodiazepine.
Original label: early. Preserved for traceability; the reviewed wording above qualifies this record.
Record selank:benefit:1 · Annotated 2026-10-01 · Review method
-
Limited safety reporting; unsupported absence inference
Review of “No sedation or dependence reported”
Short parent-Selank studies provide limited tolerability data; they cannot establish absence of sedation or dependence for the modified product.
Limitations and applicability. No reported dependence in short studies is not proof of no dependence risk; derivative not studied.
Original collected claim and review history
Original title: No sedation or dependence reported
Unlike benzodiazepines, studies didn’t report drowsiness or dependence.
Original label: early. Preserved for traceability; the reviewed wording above qualifies this record.
Record selank:benefit:2 · Annotated 2026-10-01 · Review method
-
Parent Selank rodent study; modified-form mismatch
Review of “Memory and focus”
Plain Selank affected memory measures in rats; the finding does not establish cognitive benefit for N-acetyl amidated Selank.
Limitations and applicability. Study used plain Selank in rat memory/alcohol-exposure models; derivative clinical benefit cannot be inferred.
Original collected claim and review history
Original title: Memory and focus
Improved memory and learning in animal studies.
Original label: animal. Preserved for traceability; the reviewed wording above qualifies this record.
Record selank:benefit:3 · Annotated 2026-10-01 · Review method
-
Parent-compound laboratory/small human biomarker study
Review of “Immune balance”
Plain Selank altered selected immune markers in laboratory and small human studies; clinical benefit and derivative applicability are unestablished.
Limitations and applicability. Immune biomarkers are not validated “immune balance” benefits; actual modified form is not established.
Original collected claim and review history
Original title: Immune balance
Influences immune signaling, reflecting its origin in the immune peptide tuftsin.
Original label: animal. Preserved for traceability; the reviewed wording above qualifies this record.
Record selank:benefit:4 · Annotated 2026-10-01 · Review method
The research in detail
Evidence category
Little or no published research
Small Russian studies have examined plain Selank, but the evidence is limited and does not establish effects for N-acetyl amidate or Selank acetate. FDA identifies important safety-information gaps for Selank acetate. No approval for the amidate form was verified.
Evidence is assessed claim by claim above. Regulatory approval, study design, findings and relevance are separate questions; there is no single evidence score.
Risks and unknowns. What to know first.
Collected cautions follow. These are not an exhaustive or independently validated safety assessment; claim references do not automatically support every caution.
- Reported side effects are mild, such as fatigue and nasal irritation.
- Independent safety data are thin.
What people report
-
User reports
After a first nasal dose of Selank amidate (2 sprays of 100 mcg), one user had brain fog, hot flashes, clammy skin, a racing heart, anxiety and poor sleep for 2–3 days; others in the thread reported anxiety and weeks of bad sleep on Selank and Semax.
-
User reports
Effects on sleep conflict: some say evening doses ruin their sleep, while others use it at bedtime or feel sleepy in the daytime.
Source: Peptide Critic forum, ‘Semax vs Selank vs Pinealon’ (opens in a new tab)
-
User reports
Many feel nothing; some found the N-acetyl or amidate versions weaker than plain Selank.
Source: Reddit r/Peptides, ‘Semax + Selank vs the upgraded versions’ thread (opens in a new tab)
Show all 9 cautionsShow fewer cautions
-
User reports
Some users report bad headaches and nausea from Selank (2026 thread; form not stated).
Source: Reddit r/Peptides, ‘Horrible headaches and nausea from Selank’ thread (opens in a new tab)
-
User reports
A headache the next morning after an accidental double dose of a Selank and DSIP spray.
Source: Peptide Critic forum, ‘Semax vs Selank vs Pinealon’ (opens in a new tab)
-
User reports
Brain fog or fatigue, possible allergic reactions, more anxiety in some people, and nasal irritation or nosebleeds with sprays are listed from user anecdotes.
Source: Jay Campbell, ‘Semax vs Selank Nasal Peptides’ (opens in a new tab)
-
User reports
Stinging and nosebleeds from homemade sprays made with bacteriostatic water; users recommend saline instead.
-
Regulator
The FDA lists selank acetate among bulk drug substances that may present significant safety risks in compounding (possible immune reactions from aggregation and impurities) and says it lacks important safety information.
Source: FDA, Certain bulk drug substances that may present significant safety risks (opens in a new tab)
-
Regulator
The pharmacy Tailor Made Compounding, whose clinic spray is listed above, pleaded guilty to distributing unapproved new drugs including Selank (2018–2020).
Source: US Department of Justice press release, February 2021 (opens in a new tab)
Published dosing records. What the label abroad says.
Historical label and trial records for the named product, route, population and indication. These records are not a personal schedule or a validated regimen for a catalog vial. Source attribution does not establish applicability.
Selank 0.15%
Anxiety and stress-related problems in adults, such as unexplained worry, panic, poor sleep and trouble adapting (Russia; sold without a prescription)
- Days 1–14, in each nostril
- 2 drops
- How
- Drops in the nose
- How often
- 3 times a day
- How long
- 14 days; can be repeated after 1–3 weeks
- This label covers plain Selank nose drops, not the N-Acetyl Selank Amidate the vendor sells. That chemically modified form is a different molecule: this label does not cover it, and no published study of it in people was found.
- Each dose is 2 drops of the 0.15% solution (1.5 mg per mL) in each nostril. The label does not give the dose in micrograms.
- The label says a repeat course, if needed, follows a doctor’s advice.
- In a 2014 Russian trial of 60 people with anxiety disorders (Medvedev et al.), the 30 who took Selank alone got 2.7 mg a day for 14 days.
- Not for people under 18, or during pregnancy or breastfeeding.
This schedule comes from the cited national product label. Authorization and availability can change: check the current local status and exact formulation. A research vial is not the labeled product.
Community protocols. Reported online. Not clinically validated.
Community reports Collection date: 30 Sep 2026NA-Selank Amidate users most often take about 100–300 mcg by nasal spray (ready-made sprays give 100 or 200 mcg per spray) or inject about 200–750 mcg under the skin, once or twice a day or as needed.
More about this
Reports range from 100 mcg to 1,800 mcg three times a day, and many posts don’t say which form of Selank they mean.
Nasal spray, about 100–300 mcg
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Vendor: Nootropic Source, N-Acetyl Selank Amidate Spray product page
- Forum: Reddit r/Peptides, ‘N-ACETYL SELANK AMIDATE PEPTIDE’ thread
- Forum: Reddit r/Peptides, ‘n-acteyl selank amidate application and dosing’ (2022)
- Vendor: Smarter Nootropics (information site linked from Ceretropic’s product pages), Selank page (2019, archived)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- About 100–300 mcg per dose (1–2 sprays of a 100 or 200 mcg spray)
- How often
- Once or twice a day, or as needed for stress
- Route
- Nasal spray
- Timing
- Any time; many prefer later in the day or before stressful events
- Cycle
- Some copy the Russian 2-week course, then a break; many simply use it as needed
- Mixing
- Ready-made: 10 mg or 20 mg in 10 mL (100 or 200 mcg per spray). Homemade: 10 mg vial in about 3 mL (about 300 mcg per 0.1 mL spray)
- Several nootropic vendors sell NA-Selank Amidate sprays at 100 and 200 mcg per spray with identical product text.
- Smarter Nootropics, an information site linked from Ceretropic’s product pages, suggested 250–500 mcg once or twice a day for Selank in general.
- Ready-made sprays of plain Selank are weaker per spray (for example 50 mcg per spray from American Peptides), so ‘one spray’ means very different amounts.
Sources (4)
-
VendorNootropic Source, N-Acetyl Selank Amidate Spray product page (opens in a new tab)
“One bottle of either 100mcg or 200mcg solution. Each bottle contains 10ml total volume and either 10mg or 20mg total N-Acetyl Selank Amidate Solution.”
-
ForumReddit r/Peptides, ‘N-ACETYL SELANK AMIDATE PEPTIDE’ thread (opens in a new tab)
“I’ve always stayed at very low doses like 100-300mcg and it felt the best. Higher doses did nothing special.”
-
ForumReddit r/Peptides, ‘n-acteyl selank amidate application and dosing’ (2022) (opens in a new tab)
“looks like 200 mcg dose or 0.2 mg dose is a good standard”
-
“Generally 250-500mcg taken 1-2 times per day.”
Injection under the skin, about 200–750 mcg
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Book: Dr. William Seeds, Peptide Protocols (2020), as summarized by Jay Campbell
- Forum: Reddit r/Peptides, ‘N-acetyl selank amidate dosage’ thread
- Forum: Peptide Critic forum, ‘Adamax and N-Acetyl Selank Amidate (NA Selank)’
- Forum: Reddit r/Peptides, ‘N-ACETYL SELANK AMIDATE PEPTIDE’ thread
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- About 200–750 mcg (Dr. Seeds: 300 mcg a day)
- How often
- Once a day
- Route
- Injection under the skin
- Timing
- Usually morning; some say it ruins their sleep if taken in the evening
- How long
- Weeks to months (one user 2 months)
- Ramp
- Dr. Seeds: adjust by 100–250 mcg every few days
- Mixing
- 10 mg vial + 1–3 mL bacteriostatic water
- One user felt nothing by nose but says 750 mcg injected ‘turns off anxiety’ for about 12 hours.
- Jay Campbell also cites 100–300 mcg once a day by injection.
Sources (4)
-
BookDr. William Seeds, Peptide Protocols (2020), as summarized by Jay Campbell (opens in a new tab)
“Begin with the lowest effective dose, typically 300 mcg per day for subcutaneous injection.”
-
ForumReddit r/Peptides, ‘N-acetyl selank amidate dosage’ thread (opens in a new tab)
“From everything I’ve found, it’s 100-300mcg daily. I personally find that 500mcg -700mcg is the sweet spot for me.”
-
ForumPeptide Critic forum, ‘Adamax and N-Acetyl Selank Amidate (NA Selank)’ (opens in a new tab)
“I’m currently running Adamax 400mcg and NA-Selank Amidate 750mcg, all subq.”
-
ForumReddit r/Peptides, ‘N-ACETYL SELANK AMIDATE PEPTIDE’ thread (opens in a new tab)
“For me it didn’t do anything until I injected 750mcg subQ. That has been amazing!”
Show all 7 protocolsShow fewer protocols
Plain Selank 0.15% drops (Russian pharmacy product), copying the label
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- 2–3 drops in each nostril (75 mcg per drop)
- How often
- Up to 3 times a day
- Route
- Nasal drops
- How long
- 14 days
- This is the plain form, not NA-Selank Amidate; sellers copy the Russian label, which is compiled separately.
Sources (1)
-
VendorCosmicNootropic, Selank nasal drops product page (opens in a new tab)
“The average dose is 2-3 drops in each nostril. Selank should be taken up to 3 times per day. The treatment course is 14 days.”
Morning injection with Semax, 1 mg each
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Forum: Peptide Critic forum, ‘Semax vs Selank vs Pinealon’
- Forum: Peptide Critic forum, ‘Semax vs Selank vs Pinealon’
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- About 1 mg of Selank (with 1 mg of Semax); one user takes 500–750 mcg of each
- How often
- Once a day
- Route
- Injection under the skin
- Timing
- Morning
- How long
- 4 weeks
- Cycle
- 4 weeks on, 2 weeks off
- Mixing
- 10 mg research vials
- These users don’t say whether their vials are plain or amidate Selank.
- One couple followed a YouTube stack by Nick Trigili but injected instead of using his nasal route.
Sources (2)
-
ForumPeptide Critic forum, ‘Semax vs Selank vs Pinealon’ (opens in a new tab)
“We inject Semax/Selank 1mg each daily in the morning for 4 weeks on/2 weeks off cycle.”
-
ForumPeptide Critic forum, ‘Semax vs Selank vs Pinealon’ (opens in a new tab)
“I take both in the AM. About 500-750mcg subq. Selank will absolutely ruin my sleep if I take it in the evening.”
High-dose nasal spray (Dr. Seeds’ book and forum reports)
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Book: Dr. William Seeds, Peptide Protocols (2020), as summarized by Jay Campbell
- Forum: Reddit r/Peptides, ‘N-ACETYL SELANK AMIDATE PEPTIDE’ thread
- Forum: Peptide Critic forum, ‘Semax and Caffeine’
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- 750–1,000 mcg a day split into several sprays (Seeds); one user takes 1,800 mcg three times a day
- How often
- Split through the day
- Route
- Nasal spray
- How long
- Seeds: 12 weeks
- Cycle
- Seeds: 12 weeks on, 4 weeks off, repeated as needed
- Ramp
- The 1,800 mcg user worked up from 300 mcg
- Mixing
- One user mixed 90 mg for about 900 mcg per spray
- Users on this plan say lower doses did little for them; others say higher doses add nothing.
Sources (3)
-
BookDr. William Seeds, Peptide Protocols (2020), as summarized by Jay Campbell (opens in a new tab)
“Take 750-1,000 mcg once a day via nasal spray, spread out over several doses if needed.”
-
ForumReddit r/Peptides, ‘N-ACETYL SELANK AMIDATE PEPTIDE’ thread (opens in a new tab)
“I’ve been taking 1800mcg nasally three times a day and have felt that’s the best dose for me so far (worked up from 300mcg).”
-
ForumPeptide Critic forum, ‘Semax and Caffeine’ (opens in a new tab)
“Selank/semax are fairly ineffective at low doses for my rat. Have to bump up to 750mcg nasal to notice things.”
Compounded clinic spray (plain Selank)
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Vendor: Tailor Made Compounding peptide catalog (compounding pharmacy), Selank page
- Practitioner: Ben Greenfield, peptide resources page (recommended stacks, cognitive health)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- 1–2 sprays of a 7,500 mcg per mL spray (spray size not stated); the same pharmacy’s chart also lists a 100 mcg-a-day injection
- How often
- Once a day
- Route
- Nasal spray
- Mixing
- Pharmacy-made: 3 mL nasal spray at 7,500 mcg per mL
- This was plain Selank from the Tailor Made Compounding pharmacy (2019 catalog); Ben Greenfield’s recommended-stack page repeats it word for word.
- At a typical 0.1 mL per spray this would be about 750 mcg per spray.
Sources (2)
-
VendorTailor Made Compounding peptide catalog (compounding pharmacy), Selank page (opens in a new tab)
“Suggested dosage: Spray 1 to 2 sprays intranasally once daily.”
-
PractitionerBen Greenfield, peptide resources page (recommended stacks, cognitive health) (opens in a new tab)
“Selank: 1-2 sprays nasally (7500 mcg/ml provided in a 3ml nasal spray applicator)”
Evening or bedtime use, often with DSIP
Collected report · exact form and route are only as reported below. Source date and reporter identity are not separately verified. Collection checked 30 Sep 2026; presentation annotated 2026-10-01.
- Forum: Peptide Critic forum, ‘Semax vs Selank vs Pinealon’
- Forum: Peptide Critic forum, ‘Finding Semax and Selank Nasal spray’
- Forum: Reddit r/Peptides, ‘Semax/Selank vs Adamax/Adalenk’ thread
- Forum: Reddit r/Peptides, ‘N-Acetyl Selank Amidate’ (2023)
Frequency labels describe this collection, not a measured population. Contradictory records remain available.
Details and sourcesHide details
- Dose
- About 100–250 mcg
- How often
- As needed, or nightly
- Route
- Nasal spray, or injection under the skin
- Timing
- Evening or before bed; some pair Semax in the morning with Selank later in the day
- Mixing
- Some mix Selank and DSIP in one homemade spray
- Others report the opposite: Selank in the evening ruins their sleep, or daytime use makes them want to nap.
Sources (4)
-
ForumPeptide Critic forum, ‘Semax vs Selank vs Pinealon’ (opens in a new tab)
“I take 250 mcg of Selank/Dsip each before bed”
-
ForumPeptide Critic forum, ‘Finding Semax and Selank Nasal spray’ (opens in a new tab)
“I like Semax in the morning and during the day and Selank later in the day to whind down.”
-
ForumReddit r/Peptides, ‘Semax/Selank vs Adamax/Adalenk’ thread (opens in a new tab)
“Selank is also subtle, but more of a chill tool for me. It’s great before bed.”
-
ForumReddit r/Peptides, ‘N-Acetyl Selank Amidate’ (2023) (opens in a new tab)
“I settled on 100mcg before bed”
Where the numbers come from
Plain Selank is a Russian prescription drug (0.15% nasal drops, 75 mcg per drop). The N-acetyl and N-acetyl amidate versions were made by nootropic vendors (Ceretropic sold N-Acetyl Selank Amidate powder in 30 and 60 mg vials by 2015) and have never been studied in people. Community doses are borrowed from the plain drug: Smarter Nootropics, an information site linked from Ceretropic’s pages, suggested 250–500 mcg once or twice a day; Dr. William Seeds’ 2020 book gives 300 mcg a day by injection or 750–1,000 mcg by nose; and the Tailor Made Compounding pharmacy’s clinic spray (1–2 sprays a day) was repeated by Ben Greenfield. ‘Adalank’ is a newer vendor name for NA-Selank Amidate.
Home-made sprays and serums
Home-made nasal spray. Community recipes. Not tested.
Original source recordsHide
Selank is made into home-made nasal sprays the same way as Semax, usually 5–10 mg in 5–10 mL of saline, bacteriostatic water or a mix. Reported strengths are about 100–250 mcg per spray, often 1–2 sprays once or twice a day. Community practice only.
Best evidence: Approved product: Russian Selank 0.15% nose drops (1.5 mg per mL, methylparaben preservative; 2 drops per nostril 3 times a day; opened bottle 15 days at up to 25 °C) – the reference point (covered elsewhere). Home-made sprays: community only (Reddit r/Peptides, r/Nootropics), plus one compounding pharmacy strength (Tailor Made, 7,500 mcg per mL, 3 mL, 2020).
Collected strength records
-
100 mcg per sprayCommon
Workings 2 mL + 8 mL (or 1 mL + 9 mL) = 10 mL; 10 mg ÷ 10 mL = 1 mg/mL = 1,000 mcg/mL; × 0.1 mL = 100 mcg per spray. The poster gives no spray size, so 0.1 mL is assumed (approved sprays deliver about 0.1 mL per press).
Sources (4)
-
ForumReddit r/Peptides, u/im_iggy (comment, 2026-08-12) (opens in a new tab)
“I use the 10ml nasal bottles for my 10mg of selank. Do 2ml of bac and 8ml of nasal saline solution.”
-
ForumReddit r/Peptides, u/im_iggy (comment, 2026-07-26) (opens in a new tab)
“I do 1ml of bac and then 9ml of nasal spray. Just to inbihit the growth of bacteria.”
-
ForumReddit r/Peptides, u/im_iggy (comment, 2026-08-12) (opens in a new tab)
“Then do 2 pumps each day. It’s normally good for about 1 month.”
-
ManufacturerDesmopressin Nasal Spray, USP – FDA label (Apotex), DailyMed (opens in a new tab)
“Desmopressin nasal spray pump delivers 10 mcg (0.1 mL) of desmopressin acetate per spray.”
-
-
200 mcg per spraySometimes seen
Workings 10 mg ÷ 5 mL = 2 mg/mL; × 0.1 mL = 200 mcg per spray, matching the poster’s ‘roughly 200 mcg’ from about 5 mL.
Sources (2)
-
ForumReddit r/Peptides, u/ToughPair7664 (post, 2026-08-30) (opens in a new tab)
“I just reconstituted a 10 mg bottle of Selank to use as a nasal spray.”
-
ForumReddit r/Peptides, u/ToughPair7664 (post, 2026-08-30) (opens in a new tab)
“I ended up diluting it with ~5 mL of bacteriostatic water (BAC water) total to get roughly 200 mcg per spray (0.1 mL pump).”
-
10 mg with 1–2 mL bacteriostatic water, topped up to 10 mL with saline
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
- Forum: Reddit r/Peptides, u/im_iggy (comment, 2026-08-12)
- Forum: Reddit r/Peptides, u/im_iggy (comment, 2026-08-12)
- Forum: Reddit r/Peptides, u/im_iggy (comment, 2026-07-26)
- Forum: Reddit r/Peptides, u/JZCrab (comment, 2025-10-13)
- Forum: Reddit r/Peptides, u/Legitimate_Clown (comment, 2026-07-11)
- Forum: Reddit r/Peptides, u/Jack-o-Roses (comment, 2026-08-30)
Batch: 10 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| Selank (or Semax) | 10 mg | Active |
| Bacteriostatic water | 1–2 mL | Liquid / preservative |
| Nasal saline solution | 8–9 mL | Liquid |
Method
- Dissolve the peptide in the vial with the bacteriostatic water (1 mL per vial if mixing two peptides in one bottle).
- Add it to a 10 mL nasal bottle and fill with saline.
- How it’s used
- 2 pumps a day (one poster).
- Per dose
- Not stated (spray volume not given).
- Preservative
- A small amount of bacteriostatic water ‘to inhibit the growth of bacteria’.
- Keeps for
- About 1 month; one poster uses bottles within 30 days.
- A third user makes the same kind of mix with 1 mL bacteriostatic water plus 4 mL saline.
- A long-time maker (14 years) says they have used ultrapure deionised water, saline or Xlear nasal spray as the liquid, and used bacteriostatic water only once (‘ouch’).
Sources (6)
-
ForumReddit r/Peptides, u/im_iggy (comment, 2026-08-12) (opens in a new tab)
“I use the 10ml nasal bottles for my 10mg of selank. Do 2ml of bac and 8ml of nasal saline solution.”
-
ForumReddit r/Peptides, u/im_iggy (comment, 2026-08-12) (opens in a new tab)
“Then do 2 pumps each day. It’s normally good for about 1 month.”
-
ForumReddit r/Peptides, u/im_iggy (comment, 2026-07-26) (opens in a new tab)
“I do 1ml of bac and then 9ml of nasal spray. Just to inbihit the growth of bacteria.”
-
ForumReddit r/Peptides, u/JZCrab (comment, 2025-10-13) (opens in a new tab)
“I reconstitute the peptides with BAC water. 2ml total. So 2 ml in one vial if making only Semax. Or 1ml per vial if mixing.”
-
ForumReddit r/Peptides, u/Legitimate_Clown (comment, 2026-07-11) (opens in a new tab)
“I usually do 1 mL of BAC + 4 mL of Saline.”
-
ForumReddit r/Peptides, u/Jack-o-Roses (comment, 2026-08-30) (opens in a new tab)
“I’ve used ultrapure DI, saline and my current favorite, Xlear nose spray. Been making selank & derivatives nose spray for 14 years.”
10 mg in 6 mL (3 mL bacteriostatic water + 3 mL saline): 250 mcg per 0.15 mL spray
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
- Forum: Reddit r/Peptides, u/greenpamplemousse (comment, 2025-12-19)
- Forum: Reddit r/Peptides, u/greenpamplemousse (comment, 2025-12-19)
- Forum: Reddit r/Peptides, u/technoholican (comment, 2025-12-21)
Batch: 6 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| Selank | 10 mg | Active |
| Bacteriostatic water | 3 mL | Liquid / preservative |
| Sterile saline | 3 mL | Liquid |
- How it’s used
- 2 sprays a day; 6 weeks on (2 vials), then 6 weeks off.
- Per dose
- 250 mcg per spray, with a measured spray of about 0.15 mL (stated); 40 sprays per vial.
- Preservative
- Bacteriostatic water (half the liquid).
- Storage
- Fridge (question was about fridge life).
- Keeps for
- Not stated; the poster was asking.
- A reply in the same thread advised not mixing more than a week’s worth at a time because home mixing is not aseptic.
Sources (3)
-
ForumReddit r/Peptides, u/greenpamplemousse (comment, 2025-12-19) (opens in a new tab)
“Peptide: 10 mg Selank Bacteriostatic (BA) water: 3 mL Sterile saline: 3 mL Total solution: 6 mL Measured spray volume: ~0.15 mL per actuation Peptide per spray: 250 mcg”
-
ForumReddit r/Peptides, u/greenpamplemousse (comment, 2025-12-19) (opens in a new tab)
“Sprays per vial: 40 Sprays per day: 2 Cycle: 6 weeks on (2 vials) 6 weeks off”
-
ForumReddit r/Peptides, u/technoholican (comment, 2025-12-21) (opens in a new tab)
“Don’t reconstitute more than 1 week’s worth at a time (a single 10mg vial of each) as you might need to increase concentration.”
10 mg in about 5 mL bacteriostatic water: about 200 mcg per 0.1 mL spray
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
- Forum: Reddit r/Peptides, u/ToughPair7664 (post, 2026-08-30)
- Forum: Reddit r/Peptides, u/Majalisk (comment, 2026-08-30)
Batch: about 5 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| Selank | 10 mg | Active |
| Bacteriostatic water | about 5 mL | Liquid / preservative |
- Per dose
- About 200 mcg per spray from a 0.1 mL pump (stated).
- Preservative
- Bacteriostatic water.
- After mixing, the poster was told bacteriostatic water is a bad idea in the nose; replies said the burn is ‘short-lived’ or to use 0.9% saline or sterile water instead.
Not stated: how it’s used.
Sources (2)
-
ForumReddit r/Peptides, u/ToughPair7664 (post, 2026-08-30) (opens in a new tab)
“I ended up diluting it with ~5 mL of bacteriostatic water (BAC water) total to get roughly 200 mcg per spray (0.1 mL pump).”
-
ForumReddit r/Peptides, u/Majalisk (comment, 2026-08-30) (opens in a new tab)
“It’ll just be uncomfortable, but the burn is quite short-lived”
5 mg in 6.25 mL saline: 100 mcg per 0.125 mL spray (planned)
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
- Forum: Reddit r/Peptides, u/courtpchrist (post, 2024-08-25)
- Forum: Reddit r/Peptides, u/courtpchrist (comment, 2024-08-25)
- Forum: Reddit r/Peptides, u/courtpchrist (comment, 2024-11-30)
Batch: 6.25 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| Selank | 5 mg | Active |
| Saline | 6.25 mL | Liquid |
- How it’s used
- Planned: 1 spray as needed.
- Per dose
- 100 mcg per spray, assuming 0.125 mL per spray (stated plan).
- Preservative
- None.
- The poster later said they never made it because their 30 mL glass bottle sprayed inconsistently, and took it by injection instead.
- The poster said commercial Selank sprays seemed to be 100–200 mcg per spray.
Sources (3)
-
ForumReddit r/Peptides, u/courtpchrist (post, 2024-08-25) (opens in a new tab)
“a 30ml nasal spray bottle that dispenses .1-.15ml per spray (will call it .125ml for the sake of simplicity)”
-
ForumReddit r/Peptides, u/courtpchrist (comment, 2024-08-25) (opens in a new tab)
“Yeah, that’s what ChatGPT told me, too. So I’ll stick to the 6.25ml.”
-
ForumReddit r/Peptides, u/courtpchrist (comment, 2024-11-30) (opens in a new tab)
“I never ended up making the nasal spray. My spray bottle was too wonky, it sprayed inconsistently”
Compounding pharmacy Selank nasal (Tailor Made Compounding, US)
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
Batch: 3 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| Selank | 7,500 mcg per mL | Active |
- Listed as ‘Nasal’ in the January 2020 product table (doctor price $40); spray vs drops not stated.
Not stated: how it’s used and the amount per dose.
Sources (1)
-
“Nasal 7500mcg/ml 1 x 3ml $40 Neurogenic/Neurorestorative”
50 mg N-acetyl Selank amidate in 20 mL: 250 mcg per 0.1 mL spray (worked example)
Original source-specific report. Collection checked 30 Sep 2026; presentation annotated 2026-10-01. Source date and reporter identity are not separately verified. Exact form and route are limited to the source’s description.
Batch: 20 mL
Ingredients and methodHide the recipe
Ingredients
| Ingredient | Amount | Role |
|---|---|---|
| N-acetyl Selank amidate | 50 mg | Active |
| Liquid (not specified) | 20 mL | Liquid |
- Per dose
- 250 mcg per 0.1 mL spray (stated).
- Worked example from a reply to someone who bought a 50 mg ‘aliquot’.
Not stated: how it’s used.
Sources (1)
-
ForumReddit r/Nootropics, u/whole_kernel (comment, 2025-12-07) (opens in a new tab)
“200 * 0.1ml = 20ml (need this much to make x200 0.1ml doses out of your original 50mg)”
How the method was put together, step by step with its sources
Editorial synthesis and reported strength comparison
This synthesized method combines source records. It has not been validated for preparation, sterility, compatibility, absorption or storage. Select a reported strength to inspect the arithmetic; no strength is selected for you.
100 mcg per spray
Makes 10 mL · about 95 sprays (with a 0.1 mL pump)
Synthesized quantities and equipment
- 10 mg N-Acetyl Selank Amidate
- 1–2 mL bacteriostatic water, topped up to 10 mL with saline nasal spray
- Liquid, which people disagree on: sterile saline (gentler, but no preservative), bacteriostatic water (preserved, but can burn), or a mix of the two.
- An empty metered nasal spray bottle. Many are sold as about 0.1 mL per press, but users report 0.05–0.2 mL, so check yours.
- New sterile syringes to measure and move liquid. On a U-100 insulin syringe, 100 units is 1 mL, so 1 unit is 0.01 mL.
- Alcohol prep pads, for the vial stopper and the spray tip.
Synthesized steps · not validated
- Check your pump first: spray a measured amount of water through it and count the presses. Users report about 0.05–0.2 mL per press.
- Wash your hands. Wipe the vial’s rubber stopper with an alcohol pad and let it dry before piercing it.
- With a new sterile syringe, add a little of the liquid slowly, aiming it down the inside wall of the vial, not onto the powder.
- Swirl or roll the vial gently until the powder dissolves; don’t shake it. Don’t use it if it’s cloudy, discoloured or has particles.
- Draw the dissolved peptide back into the syringe and add it gently to the spray bottle.
- Rinse the vial with a little more of the liquid and add that to the bottle too, so no peptide is left behind.
- Make the bottle up to the full batch volume with the rest of the liquid.
- Fit the pump and press it into the air until a fine mist appears; labels say 4–6 presses. Re-prime after 3–7 days unused.
- Label the bottle with the date you mixed it and its strength.
- Before each dose, blow your nose gently. Close one nostril and aim the tip toward the back of your head, not the middle wall.
- Labels differ: some say breathe in gently as you press, others hold your breath. Try not to sneeze or blow your nose straight afterwards.
- Afterwards, wipe the tip with an alcohol wipe, put the cap back on and keep the bottle upright.
- Each spray
- 100 mcg per 0.1 mL spray
- Keeps
- Fridge (2–8 °C), upright; don’t freeze. No tested shelf life: pharmacy defaults are 14 days unpreserved, 35 days preserved; saline dilutes bacteriostatic water’s preservative.
- How it’s used
- One press per nostril at a time: a nostril holds about 0.1 mL, at most 0.15 mL, and more runs out or is swallowed.
Good to know
- Bacteriostatic water contains 0.9–1.1% benzyl alcohol as a preservative. Its label covers mixing injections, not nasal use; EU labels warn of allergic reactions.
- Some use store-bought saline nasal spray for its preservatives: often benzalkonium chloride, which can irritate the nose with long use, and sometimes benzyl alcohol.
- Never tap water: it is not sterile, and CDC researchers warn against it for nasal rinsing.
This method is a guide put together from the sources cited for each item (drug labels, pharmacy and CDC rules, research reviews and community recipes); it is not anyone’s tested protocol. The method’s sources
Strengths people report
- 100 mcg per spray: 10 mg N-Acetyl Selank Amidate in 1–2 mL bacteriostatic water, topped up to 10 mL with saline nasal spray (10 mL · about 95 sprays (with a 0.1 mL pump))
- 200 mcg per spray: 10 mg N-Acetyl Selank Amidate in 5 mL bacteriostatic water (5 mL · about 45 sprays)
What people report
-
User reports
A cloudy home-made Selank spray was judged by several users to be bacterial or mould growth (‘Definitely mold’).
Source: Reddit r/Nootropics – ‘Cloudy Selank nasal spray’ (2026) (opens in a new tab)
-
User reports
Some users report fatigue or lethargy after Selank nasal spray.
Source: Reddit r/Peptides – ‘Selank fatigue?’ (2025) (opens in a new tab)
-
User reports
Several users say plain Selank spray felt like nothing (‘a more expensive saline nasal spray’) or that they needed about 700 mcg per use.
Research notes
Form confusion: most published protocols and all clinic products concern plain Selank; data specific to NA-Selank Amidate come from a handful of Reddit and forum threads. ‘Adalank’ is a marketing name for NA-Selank Amidate. Reports conflict on timing (calming at bedtime versus ruining sleep) and on dose (100–300 mcg ‘best’ versus nothing until 750 mcg, and one user at 1,800 mcg three times a day). The clinic spray’s amount per spray is not stated. Selank was not among the peptides reviewed by the FDA advisory committee in July 2026. One 2023 Reddit user describes a strong reaction to a first 200 mcg nasal dose of the amidate (possibly from uneven mixing).
Nasal spray
Shelf-life claims conflict: ‘about 7 to 10 days’ in the fridge with sterile water and ‘3 or 4 weeks’ with bacteriostatic water (one user), ‘about 1 month’ (another), ‘Stable for up to 40 days’ (another); none cite data. The same user who gave those shelf lives claimed bacteriostatic water is ‘well below anything irritating’, which contradicts many other users. Official Selank drops allow only 15 days after opening.
What it is. In plain English.
The listed N-acetyl Selank amidate is a modified seller product; studies and Russian product status for plain Selank do not establish its effects or approval.
This entry names N-acetyl Selank amidate, a modified form distinct from plain Selank and Selank acetate. Human research or any national product status for plain Selank does not establish the identity, clinical effects or approval of this amidate form.
Plain Selank has been studied for anxiety and other neuroactive effects, but proposed mechanisms and evidence are limited. This entry is the N-acetyl amidate form, and findings for plain Selank do not establish the same effects for it.
Reviewed 2026-10-01.
Structure. Nothing to show yet.
No experimental 3D structure of Selank or N-acetyl Selank amidate is in the .
Tuftsin (TKPR), its first four amino acids, appears in two entries, bound to a neuropilin and to a bacterial protein, but neither is Selank or a target of Selank.
Checked 30 Sep 2026.
Specs. The facts at a glance.
- Length
- 7 amino acids
- Sequence
- Ac-TKPRPGP-NH₂
- Sold as
- N-Acetyl Selank Amidate 10 mg
- In blends
- Selank / Semax10 mg / 10 mg per vial
- Regulatory status
- No FDA or EU approval was identified for N-acetyl Selank amidate. Any Russian nasal Selank product is a separate form; its status does not extend to this modified seller product. FDA has noted safety-information gaps for Selank acetate.
- Also known as
- Modified Selank
Sources. What this page rests on.
Every source behind this page, with what it says and when it was checked, is in the Source library.
N-Acetyl Selank Amidate in the Source library
Original overview and research notes · annotated 2026-10-01
Historical collection text. Read alongside the claim corrections above; identity or evidence qualifications may supersede this wording.
Calm without sedation
A Russian anti-anxiety peptide, sold here in a modified form.
A synthetic analog of tuftsin, a small immune peptide, extended with Pro-Gly-Pro for stability. The N-acetyl amidate form has capped ends and hasn’t been clinically studied.
It appears to enhance GABA signaling (the calming system benzodiazepines act on, through a different route), slows the breakdown of enkephalins (natural painkillers), and influences BDNF and immune signaling.
Russian trials in generalized anxiety reported effects comparable to a benzodiazepine without sedation or dependence. The studies are small and haven’t been replicated in the West.
Original status record: Approved in Russia as nasal drops for anxiety, but that product is plain Selank, not this N-acetyl amidate form. Not approved in the US or EU.